Literature summary extracted from

Okamura-Ikeda, K.; Hosaka, H.; Yoshimura, M.; Yamashita, E.; Toma, S.; Nakagawa, A.; Fujiwara, K.; Motokawa, Y.; Taniguchi, H.
Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia (2005), J. Mol. Biol., 351, 1146-1159.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.1.2.10	apoform and bound to 5-methyltetrahydrofolate	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.2.10	Homo sapiens	P48728	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
2.1.2.10	[protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3	5-methyltetrahydrofolate is bound in a kinked shape with the pteridine group deeply buried into the hydrophobic pocket ant the glutamyl group pointed to the C-terminal side surface. R292 interacts through water molecules with the folate polyglutamate tail	Homo sapiens	a

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Release 2023.1 (January 2023)